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Spironolactone
and acne
have always been looked upon as a
favorable combination. In other words, Spironolactone is
often used by dermatologists to treat acne . Spironolactone belongs to the class of
drugs known as antiandrogens. Antiandrogens are hormone
inhibitors. They work by inhibiting the biological
effects of androgens (sex hormones) by blocking the
androgen receptors on specific tissues. Even though this
class of drugs is chiefly used to correct hormonal
disbalances in the body, it has also found use in
treating acne. This is because hormonal disbalance is
one of the causes of acne.
Acne and Hormones: The
Link
Speaking of disruption in the
hormonal balance of the body, let's take a closer look
at the problem. Acne is caused by many factors. But one
of the most significant reasons is an increased
production of sex hormones in the body. A disruption in
the hormone levels of the body is not uncommon during
our adolescent years. It usually stabilizes over time,
as the person grows older, and eventually levels off.
This is the reason why in most cases, acne disappears on
its own as a person advances in age.
However, in some cases, normalcy in
the hormone levels may not be reached naturally. The
disbalance can persist, causing the triggering of the
oil glands to pump out excessive amounts of sebum or
oil. Overactive oil glands are believed to be
responsible for acne and inflammation as they promote
bacterial growth. Under such circumstances, a hormone
stabilizing drug like Spironolactone can help bring the
situation under control. It effectively blocks the
androgen receptors of the oil glands and in doing so,
stops the triggering effect caused by abnormal levels of
testosterone. Blocking of androgen receptors reduces the
volume of oil production and consequently, discourages
the growth of various bacteria, including the P. acne bacterium
which causes
acne.
It
must be borne in mind that Spironolactone does not have a
direct effect on the acne causing bacteria. It does not
kill them but prevents their excessive growth by
creating an environment which is detrimental to their
growth and proliferation. This is done by reducing the
amount of sebum secreted by the body, which promotes the
bacterial growth.
Spironolactone: Does it REALLY
Work?
Just
like most other conventional drugs, Spironolactone too,
comes with a few words of caution. Spironolactone cannot
be used by everybody. One drawback of using
Spironolactone is that it cannot be administered to male
patients because it can severely affect the secondary
sex characteristics of males. The toleration to this
drug also varies from individual to individual. You are
well advised to consult with your dermatologist before
starting on a course of
Spironolactone.
One
problem with drugs like Spironolactone is that
they tend to look at the problem of acne from one
dimension. And this is why Spironolactone and
acne cure is not always a happy relationship.
While hormonal disbalance is a major cause of acne , it is not the only one. There are other
factors too. Opt for the holistic mode of treatment for
a fuller and more complete approach towards removing
acne from your life. The holistic approach is more
successful because it treats the body as a whole and
fights all the causes of acne, rather than just the
symptoms of the problem. Talk to your doctor today about
the holistic way and get well naturally, without
side-effects and expensive
medication.
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